Modulation of cytosolic Ca2+ concentration by nordihydroguaiaretic acid in porcine coronary arterial smooth muscle cells
نویسندگان
چکیده
منابع مشابه
Cytosolic calcium transients differ between porcine coronary arterial and aortic smooth muscle cells in primary culture.
Using quin 2 microfluorometry of porcine vascular smooth muscle cells in primary culture at 25 degrees C, we investigated differences in cytosolic calcium transients between epicardial coronary artery and aorta. Both in coronary arterial and aortic smooth muscle cells, histamine induced transient and dose-dependent elevations of cytosolic calcium concentrations, with a similar time course and E...
متن کاملRole of smooth muscle cells on endothelial cell cytosolic free calcium in porcine coronary arteries.
We tested the hypothesis that the cytosolic free calcium concentration in endothelial cells is under the influence of the smooth muscle cells in the coronary circulation. In the left descending branch of porcine coronary arteries, cytosolic free calcium concentration ([Ca(2+)](i)) was estimated by determining the fluorescence ratio of two calcium probes, fluo 4 and fura red, in smooth muscle an...
متن کاملEstrogen increases Ca2+efflux from female porcine coronary arterial smooth muscle.
Acute estrogen administration relaxes vascular smooth muscle by decreasing intracellular Ca2+ concentration ([Ca2+]i). In the present study, we examined the hypothesis that this reduction in [Ca2+]iis mediated in part by enhanced Ca2+ efflux. Coronary artery smooth muscle cells were isolated from gonad-intact, sexually mature female pigs. The [Ca2+]iresponse to endothelin-1 was measured using f...
متن کاملDiadenosine polyphosphates directly relax porcine coronary arterial smooth muscle.
By use of front-surface fluorometry and fura-2-loaded medial strips of the porcine coronary artery, cytosolic Ca++ concentration ([Ca++]i) and force development were monitored simultaneously to determine the mechanisms of vasorelaxation induced by the diadenosine polyphosphates (APnA) diadenosine 5',5'''-P1, P4-tetraphosphate (AP4A) and diadenosine 5',5'''-P1,P5-pentaphosphate (AP5A). APnA conc...
متن کاملMechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells
Citation: Qian L-L, Sun M-Q, Wang R-X, Lu T, Wu Y, Dang S-P, Tang X, Ji Y, Liu X-Y, Zhao X-X, Wang W, Chai Q, Pan M, Yi F, Zhang D-M and Lee H-C (2018) Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial Smooth Muscle Cells. Front. Pharmacol. 9:223. doi: 10.3389/fphar.2018.00223 Mechanisms of BK Channel Activation by Docosahexaenoic Acid in Rat Coronary Arterial...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)34366-5